Layer
Microsoft Agent 365 Identity and registry of the agent
RenLayer Inline proxy in front of every LLM call
Primary scope
Microsoft Agent 365 Who the agent is and what it can access
RenLayer What the agent sends and receives
Provider neutrality
Microsoft Agent 365 Built around Microsoft 365, Entra and Purview
RenLayer Provider-agnostic across OpenAI, Anthropic, Bedrock, Vertex, Mistral and OSS
Granularity
Microsoft Agent 365 Agents, tenants, organizations
RenLayer LLM calls, tokens, prompts and content payloads
Control timing
Microsoft Agent 365 Observes and audits after the fact. Runtime controls via Intune and Defender are in public preview (Jun 2026).
RenLayer Inspects and blocks each request with negligible latency before it leaves your network
Deployment
Microsoft Agent 365 Requires the Agent 365 SDK or Cloud PC instrumentation. Agents must be onboarded.
RenLayer Point your agent at the RenLayer endpoint. No SDK, no code change.
Pricing model
Microsoft Agent 365 $15 per user per month, included in the M365 E7 SKU
RenLayer Usage-based on agent activity, independent of seat licenses
Agent code audit
Microsoft Agent 365 Out of scope. Agent 365 governs the agent identity, not the source code the agent is written in.
RenLayer Connect a GitHub repo: secrets, prompt-injection patterns, runaway tool loops and vulnerable dependencies surfaced before deployment, with per-finding cost-impact estimates.
MCP server audit
Microsoft Agent 365 Out of scope. Agent 365 does not analyse the third-party MCP code the agent runs.
RenLayer Submit any GitHub URL: multi-layer security review across code, dependencies, secrets and misconfiguration, with an AI-synthesized risk verdict before integration.
Shadow AI discovery
Microsoft Agent 365 Out of scope. Agent 365 governs the agents you register; it does not surface the unsanctioned LLM use happening in employees' browsers.
RenLayer Browser extension plus egress capture surface every unsanctioned ChatGPT, Claude, Gemini or Copilot call, attributed to user, team and department, with per-conversation risk scoring.
Toxic combination detection
Microsoft Agent 365 Out of scope. No activity graph of which agents reach which sensitive data, and no detection of the lethal trifecta.
RenLayer A live activity graph maps which agents, models and tools reach which sensitive data, and flags the lethal trifecta (untrusted input, sensitive data, autonomous action) before it completes, with GDPR and EU AI Act references.
Best for
Microsoft Agent 365 Microsoft-first organizations standardizing on Copilot Studio and Foundry
RenLayer Multi-cloud, multi-model agent fleets where compliance and DLP must hold across providers